Clinical applications of dynamic susceptibility contrast perfusion-weighted MR imaging in brain tumours
| Autor: | Romano, Andrea, Mcr, Espagnet, ROSSI ESPAGNET, MARIA CAMILLA, Calabria, L. F., Coppola, V., Talamanca, L. F., Figa Talamanca, L., Cipriani, V., Pierallini, Alberto, Fantozzi, Luigi Maria, Bozzao, Alessandro, Minniti, Giuseppe |
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| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Central nervous system Contrast Media Hemodynamics Perfusion scanning Magnetic resonance imaging Vascularity medicine Humans Radiology Nuclear Medicine and imaging brain tumours perfusion neuroradiology magnetic resonance imaging Neuroradiology Brain tumours Perfusion medicine.diagnostic_test Brain Neoplasms business.industry General Medicine medicine.anatomical_structure Cerebral blood flow Cerebrovascular Circulation Radiology medicine.symptom business Magnetic Resonance Angiography |
| Zdroj: | La radiologia medica. 117:445-460 |
| ISSN: | 1826-6983 0033-8362 |
| DOI: | 10.1007/s11547-011-0715-4 |
| Popis: | Magnetic resonance imaging (MRI) with a dynamic susceptibility contrast perfusion-weighted imaging (DSC-PWI) sequence to study brain tumours provides information on the haemodynamic characteristics of the neoplastic tissue. Brain perfusion maps and calculation of perfusion parameters, such as relative cerebral blood flow (rCBF), relative cerebral blood volume (rCBV) and mean transit time (MTT) allow assessment of vascularity and angiogenesis within tumours of the central nervous system (CNS), thus providing additional information to conventional MRI sequences. Although DSC-PWI has long been used, its clinical use in the study of brain tumours in daily clinical practice is still to be defined. The aim of this review was to analyse the application of perfusion MRI in the study of brain tumours by summarising our personal experience and the main results reported in the literature. |
| Databáze: | OpenAIRE |
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