The genetic basis of disease
| Autor: | Leah Marks, Maria Jackson, Gerhard May, Joanna B. Wilson |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Single gene Genomics Disease Computational biology Biology Biochemistry Polymerase Chain Reaction Corrections Molecular Bases of Health & Disease Epigenesis Genetic 03 medical and health sciences chemistry.chemical_compound Human disease Neoplasms medicine Animals Humans genetics Epigenetics Molecular Biology Cancer Chromosome Aberrations Genome Human Mosaicism Genetic Diseases Inborn Genetic Variation DNA molecular basis of health and disease medicine.disease Disease Models Animal 030104 developmental biology chemistry Mutation |
| Zdroj: | Essays in Biochemistry |
| ISSN: | 0071-1365 |
| Popis: | Genetics plays a role, to a greater or lesser extent, in all diseases. Variations in our DNA and differences in how that DNA functions (alone or in combinations), alongside the environment (which encompasses lifestyle), contribute to disease processes. This review explores the genetic basis of human disease, including single gene disorders, chromosomal imbalances, epigenetics, cancer and complex disorders, and considers how our understanding and technological advances can be applied to provision of appropriate diagnosis, management and therapy for patients. |
| Databáze: | OpenAIRE |
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