An Inhibitor of Trypsin-Like Activity in Rat Liver
| Autor: | Celia Kaye, Danica Dabich |
|---|---|
| Rok vydání: | 1969 |
| Předmět: |
Chromatography
Chemical Phenomena Chemistry Caseins Tryptic hydrolysis Hydrogen-Ion Concentration Naphthalenes Arginine Trypsin General Biochemistry Genetics and Molecular Biology Rats Hydrolysis Liver Biochemistry Microsomes Rat liver Casein medicine Microsome Animals Lysosomes Trypsin Inhibitors Digestion medicine.drug |
| Zdroj: | Experimental Biology and Medicine. 131:1366-1368 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-131-34108 |
| Popis: | SummaryInhibitors of lysosomal and tryptic hydrolysis of benzoyl-dl-arginine-β-naphthylamide (BANA) were shown to be present in the microsomal and 100,000g supernatant fractions of rat liver homogenates. The 100,000g soluble inhibitor was shown to be: (1) capable of inhibiting tryptic digestion of casein and BANA; (2) insoluble at pH 4.0 but soluble at neutral or basic pH values; (3) nondialyzable; and (4) heat-stable. The inhibitor was maximally active at pH 7.4 and above during lysosomal hydrolysis of BANA. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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