Assessment of Quality of Life in Young Patients with Single Ventricle after the Fontan Operation
| Autor: | Karen Uzark, Victor Zak, Peter Shrader, Brian W. McCrindle, Elizabeth Radojewski, James W. Varni, Kaitlyn Daniels, Jill Handisides, Kevin D. Hill, Linda M. Lambert, Renee Margossian, Victoria L. Pemberton, Wyman W. Lai, Andrew M. Atz, Gail Pearson, Mario Stylianou, Jonathan Kaltman, Lynn Sleeper, Steven Colan, Dianne Gallagher, Lynn Mahony, Jane Newburger, Roger Breitbart, Carolyn Dunbar-Masterson, Lisa-Jean Buckley, Bethany Trainor, Rosalind Korsin, Robert Shaddy, J. William Gaynor, Stephen M. Paridon, Tonia Morrison, Nicole Mirarchi, Jennifer S. Li, Piers Barker, Mingfen Xu, J. Philip Saul, Patricia Infinger, Ann Harvey Frampton, LuAnn Minich, Richard Williams, Linda Lambert, Brian McCrindle, Svetlana Khaikin, Patricia Walter, Bradley Marino, Michael Artman, Timothy Feltes, Julie Johnson, Jeffrey Krischer, G. Paul Matherne, Nakela Cook, John Kugler, David Gordon, David J. Driscoll, Mark Galantowicz, Sally A. Hunsberger, Holly Taylor, Thomas J. Knight, Catherine L. Webb |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Pediatrics SF-36 Adolescent Cross-sectional study medicine.medical_treatment Psychological intervention 030204 cardiovascular system & hematology Fontan Procedure Article Fontan procedure 03 medical and health sciences Young Adult 0302 clinical medicine Quality of life 030225 pediatrics Surveys and Questionnaires medicine Humans Survivors Young adult business.industry Age Factors humanities United States Cross-Sectional Studies Pediatrics Perinatology and Child Health Cohort Physical therapy Quality of Life Female business Psychosocial Follow-Up Studies |
| Zdroj: | The Journal of pediatrics. 170 |
| ISSN: | 1097-6833 |
| Popis: | To assess self-reported quality of life (QOL) in a large multicenter cohort of adolescent and young adults surviving Fontan.Cross-sectional. The Pediatric Quality of Life Inventory (PedsQL) was administered to 408 survivors of Fontan ages 13-25 years enrolled in the Pediatric Heart Network Fontan Follow-up Study. Subjects also completed either the Child Health Questionnaire (age19 years) or Short Form Health Survey (age ≥ 19 years). PedsQL data were compared with matched controls without a chronic health condition. Correlations between the measures were examined.Mean PedsQL scores for subjects receiving Fontan were significantly lower than those for the control group for physical and psychosocial QOL (P.001). Overall, 45% of subjects receiving Fontan had scores in the clinically significant impaired range for physical QOL with 30% in the impaired range for psychosocial QOL. For each 1 year increase in age, the physical functioning score decreased by an average of 0.76 points (P = .004) and the emotional functioning score decreased by an average of 0.64 points (P = .03). Among subjects ≥19 years of age, the physical functioning score decreased by an average of 2 points for each year increase in age (P = .02). PedsQL scale scores were significantly correlated with conceptually related Child Health Questionnaire (P.001) and Short Form Health Survey scores (P.001).Survivors of Fontan are at risk for significantly impaired QOL which may decline with advancing age. Routine assessment of QOL is essential to inform interventions to improve health outcomes. The PedsQL allowed QOL assessment from pediatrics to young adulthood.ClinicalTrials.gov: NCT00132782. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect