Interpretation of a marker chromosome 17p in multiple myeloma
| Autor: | F. Shabtai, I. Halbrecht |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Genetic Markers
Male Genetics Marker chromosome Chromosomal translocation General Medicine Middle Aged Biology medicine.disease Molecular biology Chromosome Banding Chromosome 17 (human) Chromosome (genetic algorithm) Karyotyping medicine Humans Female Multiple Myeloma Multiple myeloma Aged Chromosomes Human 16-18 |
| Zdroj: | Hereditas. 95:11-14 |
| ISSN: | 0018-0661 |
| DOI: | 10.1111/j.1601-5223.1981.tb01322.x |
| Popis: | Sixteen patients with multiple myeloma (MM) have been studied cytogenetically. Chromosome 14 was the chromosome most often involved in structural aberrations. Chromosome 17 was involved in numerical aberrations and its short arm was frequently damaged at p12, giving the chromosome a satellited appearance, similar to that found in healthy people with a familial heteromorphic 17p. In our opinion the change in the 17p marker in MM represents a constriction (site of viral modification?) and is not a translocation. |
| Databáze: | OpenAIRE |
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