Pulsatile flow in ventricular catheters for hydrocephalus
| Autor: | U. Thomale, José Valero, M. U. Schuhmann, Marcelo Galarza, Ángel Giménez, José M. Amigó |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
General Mathematics 0206 medical engineering Pulsatile flow General Physics and Astronomy 02 engineering and technology Computational fluid dynamics Prosthesis Design Models Biological Ventriculoperitoneal Shunt Cerebral Ventricles 03 medical and health sciences 0302 clinical medicine Cerebrospinal fluid Catheters Indwelling Internal medicine Catheterization Peripheral medicine Animals Humans Computer Simulation Boundary value problem Cerebrospinal Fluid business.industry General Engineering Blood flow Articles medicine.disease 020601 biomedical engineering Ventricular catheter Hydrocephalus Equipment Failure Analysis Flow (mathematics) Pulsatile Flow Cardiology business Rheology 030217 neurology & neurosurgery |
| Popis: | The obstruction of ventricular catheters (VCs) is a major problem in the standard treatment of hydrocephalus, the flow pattern of the cerebrospinal fluid (CSF) being one important factor thereof. As a first approach to this problem, some of the authors studied previously the CSF flow through VCs under time-independent boundary conditions by means of computational fluid dynamics in three-dimensional models. This allowed us to derive a few basic principles which led to designs with improved flow patterns regarding the obstruction problem. However, the flow of the CSF has actually a pulsatile nature because of the heart beating and blood flow. To address this fact, here we extend our previous computational study to models with oscillatory boundary conditions. The new results will be compared with the results for constant flows and discussed. It turns out that the corrections due to the pulsatility of the CSF are quantitatively small, which reinforces our previous findings and conclusions. This article is part of the themed issue ‘Mathematical methods in medicine: neuroscience, cardiology and pathology’. |
| Databáze: | OpenAIRE |
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