Whole-body MRI to assess bone involvement in prostate cancer and multiple myeloma: comparison of the diagnostic accuracies of the T1, short tau inversion recovery (STIR), and high b-values diffusion-weighted imaging (DWI) sequences
| Autor: | Vassiliki Pasoglou, Frédéric Lecouvet, Ahmed Larbi, Patrick Omoumi, Perrine Triqueneaux, Catherine Cyteval, Bertrand Tombal, Nicolas Michoux |
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| Přispěvatelé: | Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain = Catholic University of Louvain (UCL), Cliniques Universitaires Saint-Luc [Bruxelles], Centre Hospitalier Universitaire Vaudois [Lausanne] (CHUV), Hôpital Lapeyronie [Montpellier] (CHU), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation, UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - (SLuc) Service de radiologie, UCL - (SLuc) Service d'urologie, UCL - SSS/IONS/NEUR - Clinical Neuroscience |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Whole body imaging Bone Neoplasms 030218 nuclear medicine & medical imaging Metastasis 03 medical and health sciences Prostate cancer 0302 clinical medicine Magnetic resonance imaging Bone Marrow Multiple myeloma Humans Medicine Radiology Nuclear Medicine and imaging cardiovascular diseases Neoplasm Metastasis Aged Neoplasm Staging Neuroradiology Aged 80 and over Bone marrow diseases medicine.diagnostic_test Receiver operating characteristic business.industry Prostatic Neoplasms General Medicine Middle Aged medicine.disease 3. Good health Diffusion Magnetic Resonance Imaging ROC Curve 030220 oncology & carcinogenesis Radiology business [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology Diffusion MRI |
| Zdroj: | European Radiology European Radiology, Springer Verlag, 2019, 29 (8), pp.4503-4513. ⟨10.1007/s00330-018-5796-1⟩ European Radiology, Vol. 29, no. 8, p. 4503-4513 (2019) |
| ISSN: | 0938-7994 1432-1084 |
| Popis: | To compare the diagnostic accuracy of whole-body T1, short tau inversion recovery (STIR), high b-value diffusion-weighted imaging (DWI), and sequence combinations to detect bone involvement in prostate cancer (PCa) and multiple myeloma (MM) patients. We included 50 consecutive patients with PCa at high risk for metastasis and 47 consecutive patients with a histologically confirmed diagnosis of MM who received whole-body MRI at two institutions from January to December 2015. Coronal T1, STIR, and reconstructed coronal high b-values DWI were obtained for all patients. Two musculoskeletal radiologists read individual sequences, pairs of sequences (T1-DWI, T1-STIR, and STIR-DWI), and all combined (T1-STIR-DWI) to detect bone involvement. Receiver operating characteristic curve analysis was used to assess diagnostic performance according to a “best valuable comparator” combining baseline and 6-month imaging and clinical and biological data. Interobserver agreement was calculated. Interobserver agreement for individual and combined MRI sequences was very good in the PCa group and ranged from good to very good in the MM group (0.76–1.00). In PCa patients, T1-DWI, T1-STIR, and T1-STIR-DWI showed the highest performance (sensitivity = 100% [95% CI = 90.5–100%], specificity = 100% [75.3–100%]). In MM patients, the highest performance was achieved by T1-STIR-DWI (sensitivity = 100% [88.4–100%], specificity = 94.1% [71.3–100%]). T1-STIR-DWI significantly outperformed all sequences (p |
| Databáze: | OpenAIRE |
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