Effect of smoking and comorbidities on survival in idiopathic pulmonary fibrosis
| Autor: | Hanna Nurmi, Tuomas A. Selander, Miia Kärkkäinen, Hannu-Pekka Kettunen, Minna Purokivi, Riitta Kaarteenaho |
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| Přispěvatelé: | School of Medicine / Clinical Medicine |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Younger age morbidity Idiopathic pulmonary fibrosis Disease Comorbidity smoking 03 medical and health sciences 0302 clinical medicine Internal medicine gender Medicine Humans 030212 general & internal medicine Lung cancer Survival rate Aged Retrospective Studies Aged 80 and over COPD business.industry Research Smoking Retrospective cohort study Middle Aged medicine.disease idiopathic pulmonary fibrosis respiratory tract diseases Survival Rate comorbidity 030228 respiratory system genderco Physical therapy behavior and behavior mechanisms Female business |
| Zdroj: | Respiratory Research |
| Popis: | Background Cigarette smoking has been associated with the risk of idiopathic pulmonary fibrosis (IPF). Certain comorbidities have been associated with reduced survival although some studies have indicated that current smokers have a longer survival than ex-smokers. Comorbidities in relation to smoking history have not been previously analyzed. Methods Retrospective data was collected and patients were categorized according to gender and smoking habits. Comorbidities and medications were collected. Predictive values for mortality were identified by COX proportional hazard analyses. Results We examined 45 non-smokers (53.3% female), 66 ex-smokers (9.1% female) and 17 current smokers (17.6% female) with IPF. Current smokers were younger at baseline (58.1 ± 8.74 years) compared to non-smokers (71.4 ± 8.74, p < 0.001) and ex-smokers (72.5 ±7.95, p published version peerReviewed |
| Databáze: | OpenAIRE |
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