5-Methyltetrahydrofolate level in the serum of depressed subjects and its relationship to the outcome of ECT
| Autor: | Gillian Farrar, M.T. Abou-Saleh, M. Wesson, J.A. Blair, R. J. Leeming, D. N. Anderson, Andrew M. Wilkinson |
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| Rok vydání: | 1994 |
| Předmět: |
Depressive Disorder
medicine.medical_specialty Treatment response medicine.medical_treatment 5-Methyltetrahydrofolate behavioral disciplines and activities Gastroenterology Response to treatment Psychiatry and Mental health Clinical Psychology Treatment Outcome Electroconvulsive therapy Blood serum Internal medicine mental disorders Healthy volunteers medicine Humans Electroconvulsive Therapy Electroconvulsive shock therapy Psychiatry Psychology Tetrahydrofolates Depression (differential diagnoses) Aged |
| Zdroj: | Journal of Affective Disorders. 32:163-168 |
| ISSN: | 0165-0327 |
| DOI: | 10.1016/0165-0327(94)90014-0 |
| Popis: | Serum 5-MeTHF levels are reported in 26 subjects, before and after completing a course of ECT, and compared to 21 healthy volunteers. 5-MeTHF levels of depressed subjects were significantly lower than controls before and after ECT. There was no difference in 5-MeTHF levels between ECT responders and non-responders but folate deficiency was related to severity of depression before ECT. Serum 5-MeTHF was not related to treatment response and values remained markedly low even after a good response to treatment. |
| Databáze: | OpenAIRE |
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