Fast diffusion imaging with high angular resolution
| Autor: | Stephan E. Maier, Bruno Madore, Jr Yuan George Chiou, Tzu Cheng Chao |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Similarity (geometry) Computer science Article 030218 nuclear medicine & medical imaging 03 medical and health sciences Acceleration 0302 clinical medicine Optics Sampling (signal processing) Image Processing Computer-Assisted medicine Humans Radiology Nuclear Medicine and imaging Angular resolution Computer vision Diffusion (business) medicine.diagnostic_test business.industry Brain Magnetic resonance imaging Data Compression Diffusion Magnetic Resonance Imaging Compressed sensing Female Artificial intelligence business Algorithms 030217 neurology & neurosurgery Data compression |
| Zdroj: | Magnetic Resonance in Medicine. 77:696-706 |
| ISSN: | 1522-2594 0740-3194 |
| Popis: | Purpose High angular resolution diffusion imaging (HARDI) is a well-established method to help reveal the architecture of nerve bundles, but long scan times and geometric distortions inherent to echo planar imaging (EPI) have limited its integration into clinical protocols. Methods A fast imaging method is proposed here that combines accelerated multishot diffusion imaging (AMDI), multiplexed sensitivity encoding (MUSE), and crossing fiber angular resolution of intravoxel structure (CFARI) to reduce spatial distortions and reduce total scan time. A multishot EPI sequence was used to improve geometrical fidelity as compared to a single-shot EPI acquisition, and acceleration in both k-space and diffusion sampling enabled reductions in scan time. The method is regularized and self-navigated for motion correction. Seven volunteers were scanned in this study, including four with volumetric whole brain acquisitions. Results The average similarity of microstructural orientations between undersampled datasets and their fully sampled counterparts was above 85%, with scan times below 5 min for whole-brain acquisitions. Up to 2.7-fold scan time acceleration along with four-fold distortion reduction was achieved. Conclusion The proposed imaging strategy can generate HARDI results with relatively good geometrical fidelity and low scan duration, which may help facilitate the transition of HARDI from a successful research tool to a practical clinical one. Magn Reson Med 77:696-706, 2017. © 2016 International Society for Magnetic Resonance in Medicine. |
| Databáze: | OpenAIRE |
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