Perinatal risk factors associated with central retinal changes in former preterm children on optical coherence tomography angiography

Autor: Rupesh Agrawal, Sarakshi Mahajan, Manca Tekavčič Pompe, Alenka Lavric, Spela Markelj, Jianbin Ding
Rok vydání: 2021
Předmět:
Zdroj: Acta ophthalmologicaReferences. 100(1)
ISSN: 1755-3768
Popis: PURPOSE To assess the association between perinatal risk factors for retinopathy of prematurity (ROP) and central retinal structures of former preterm children seen on optical coherence tomography angiography (OCTA). METHODS This prospective cohort study included 40 children with a history of preterm birth and 33 healthy full-term children. We documented their birth weight, gestational age, other significant risk factors for ROP development and presence of ROP. Imaging was performed using swept-source OCTA, and quantitative evaluation was performed. Analytic parameters included the area of foveal avascular zone (FAZ), foveal depth (FD), central subfoveal retinal thickness (CSFT) and capillary density index (CDI) of the deep and superficial capillary plexus. RESULTS Preterm children had significantly smaller FAZ, lower FD and higher CSFT compared to controls (all p
Databáze: OpenAIRE