Female dietary antioxidant intake and time to pregnancy among couples treated for unexplained infertility
| Autor: | Marlene B. Goldman, Richard H. Reindollar, Elizabeth H. Ruder, Terryl J. Hartman |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Infertility medicine.medical_specialty Antioxidants Article Cohort Studies Young Adult Pregnancy medicine Humans Prospective Studies Prospective cohort study Unexplained infertility Gynecology business.industry Obstetrics Female infertility Hazard ratio Obstetrics and Gynecology Middle Aged medicine.disease Time-to-Pregnancy Treatment Outcome Reproductive Medicine Dietary Reference Intake Dietary Supplements Female business Infertility Female Live Birth Body mass index |
| Zdroj: | Fertility and Sterility. 101:759-766 |
| ISSN: | 0015-0282 |
| DOI: | 10.1016/j.fertnstert.2013.11.008 |
| Popis: | To determine whether increased antioxidant intake in women is associated with shorter time to pregnancy (TTP) among a cohort of couples being treated for unexplained infertility.Secondary data analysis of a randomized controlled trial.Academic medical center associated with a private infertility center.Females with unexplained infertility.None.The time it took to establish a pregnancy that led to a live birth.Mean nutrient intake exceeded the estimated average requirement (EAR) for vitamins C and E. No differences in mean intake of any of the antioxidants were noted between women who delivered a live-born infant during the study period vs. those who did not. In multivariable models, intake of β-carotene from dietary supplements was associated with shorter TTP among women with body mass index (BMI) ≥25 kg/m(2) (hazard ratio [HR] 1.29, 95% confidence interval [CI] 1.09-1.53) and women35 y (HR 1.19, 95% CI 1.01-1.41). Intake of vitamin C from dietary supplements was associated with shorter TTP among women with BMI25 kg/m(2) (HR 1.09, 95% CI 1.03-1.15) and women35 y (HR 1.10, 95% CI 1.02-1.18). Intake of vitamin E from dietary supplements among women ≥35 y also was associated with shorter TTP (HR 1.07, 95% CI 1.01-1.13).Shorter TTP was observed among women with BMI25 kg/m(2) with increasing vitamin C, women with BMI ≥25 kg/m(2) with increasing β-carotene, women35 y with increasing β-carotene and vitamin C, and women ≥35 y with increasing vitamin E.NCT00260091. |
| Databáze: | OpenAIRE |
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