Kaposi Sarcoma of the eyelid as an initial manifestation of AIDS
| Autor: | Robert Badura, Ana Isabel Teixeira, Paulo Leal Filipe, João Borges-Costa, Miguel Neno |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Systemic disease Pathology medicine.medical_specialty Lung Neoplasms Dermatology Eyelid Neoplasms Asymptomatic Polyethylene Glycols 03 medical and health sciences 0302 clinical medicine Acquired immunodeficiency syndrome (AIDS) Antiretroviral Therapy Highly Active medicine Humans 030212 general & internal medicine Sarcoma Kaposi Acquired Immunodeficiency Syndrome Immune status Antibiotics Antineoplastic business.industry kaposi´s sarcoma disseminated AIDS General Medicine medicine.disease medicine.anatomical_structure Palpebral fissure Doxorubicin 030220 oncology & carcinogenesis HIV-1 Multiple Pulmonary Nodules Female Radiography Thoracic Eyelid Sarcoma medicine.symptom Tomography X-Ray Computed business Inferior left |
| Zdroj: | Europe PubMed Central Scopus-Elsevier Teixeira, Ana Isabel; Neno, Miguel; Badura, Robert; Borges-Costa, João; & Filipe, Paulo Leal. (2016). Kaposi Sarcoma of the eyelid as an initial manifestation of AIDS. Dermatology Online Journal, 22(7). Retrieved from: http://www.escholarship.org/uc/item/2jw6t7cs |
| ISSN: | 1087-2108 |
| DOI: | 10.5070/d3227031649 |
| Popis: | Kaposi sarcoma (KS) is a multifocal systemic disease that originates in the vascular endothelium related to Human Herpes Virus 8 (HHV-8). In the early 1980s the first series of cases of disseminated Kaposi Sarcoma in HIV infected patients were reported. However, with the advent of highly active antiretroviral therapy (HAART) since 1997, these cases are less frequently observed by clinicians. We report the case of a 40-year-old woman, presenting with two asymptomatic purpuric nodules localized in the superior and inferior left eyelids, occluding the palpebral fissure, which were present for 4 months prior to presentation. The eyelid nodules were determined to represent KS, but there were no additional cutaneous lesions. Pulmonary and gastric KS involvement was documented. Antiretroviral therapy was initiated along with pegylated liposomal doxorubicin. The nodules gradually disappeared and her immune status eventually improved. Ocular and periorbital involvement of KS associated with HIV-1 infection as the initial clinical manifestations is a rare advent. This case is important as it illustrates that disseminated KS was not to be predicted by the number or the extension of cutaneous lesions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|