Distinct phase-amplitude couplings distinguish cognitive processes in human attention
| Autor: | Ravi V. Chacko, Maurizio Corbetta, Nicholas V. Metcalf, Byungchan Kim, Suh Woo Jung, Eric C. Leuthardt, Jarod L. Roland, Gordon L. Shulman, Amy L. Daitch |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult Visual perception Cognitive Neuroscience Cued attention Phase-amplitude coupling Reaction time Sharp waves Neurology Medical and Health Sciences Article Task (project management) 03 medical and health sciences 0302 clinical medicine Rhythm Computer-Assisted Clinical Research Behavioral and Social Science medicine Humans Attention Electrocorticography Cued speech Cerebral Cortex Epilepsy Neurology & Neurosurgery medicine.diagnostic_test Psychology and Cognitive Sciences Neurosciences Contrast (statistics) Signal Processing Computer-Assisted Cognition Brain Waves 030104 developmental biology Amplitude Space Perception Signal Processing Visual Perception Cues Psychology Neuroscience 030217 neurology & neurosurgery Psychomotor Performance |
| Zdroj: | NeuroImage |
| Popis: | Spatial attention is the cognitive function that coordinates the selection of visual stimuli with appropriate behavioral responses. Recent studies have reported that phase-amplitude coupling (PAC) of low and high frequencies covaries with spatial attention, but differ on the direction of covariation and the frequency ranges involved. We hypothesized that distinct phase-amplitude frequency pairs have differentiable contributions during tasks that manipulate spatial attention. We investigated this hypothesis with electrocorticography (ECoG) recordings from participants who engaged in a cued spatial attention task. To understand the contribution of PAC to spatial attention we classified cortical sites by their relationship to spatial variables or behavioral performance. Local neural activity in spatial sites was sensitive to spatial variables in the task, while local neural activity in behavioral sites correlated with reaction time. We found two PAC frequency clusters that covaried with different aspects of the task. During a period of cued attention, delta-phase/high-gamma (DH) PAC was sensitive to cue direction in spatial sites. In contrast, theta-alpha-phase/beta-low-gamma-amplitude (TABL) PAC robustly correlated with future reaction times in behavioral sites. Finally, we investigated the origins of TABL PAC and found it corresponded to behaviorally relevant, sharp waveforms, which were also coupled to a low frequency rhythm. We conclude that TABL and DH PAC correspond to distinct mechanisms during spatial attention tasks and that sharp waveforms are elements of a coupled dynamical process. |
| Databáze: | OpenAIRE |
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