Jolkinolide D pharmacophore: synthesis and reaction with biomolecules
| Autor: | Yui Takayanagi, Hideo Kigoshi, Hiroki Shimogawa, Akira Sakakura |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
chemistry.chemical_classification
Stereochemistry Biomolecule Organic Chemistry Chemical modification General Medicine Alkylation Combinatorial chemistry Biochemistry Terpenoid Amino acid Terpene chemistry.chemical_compound chemistry Drug Discovery Organic chemistry Reactivity (chemistry) Pharmacophore DNA |
| Zdroj: | Tetrahedron. 60:7067-7075 |
| ISSN: | 0040-4020 |
| DOI: | 10.1016/j.tet.2003.08.080 |
| Popis: | To obtain information on the chemical modification of biomolecules with jolkinolide D, a bioactive diterpenoid of plant origin, jolkinolide D pharmacophore was synthesized, and its reactivity toward amino acids, nucleosides, and DNA was investigated. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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