Epidemiology, clinical manifestations, and molecular typing of salmonella typhi isolated from patients with typhoid fever in Lebanon
Autor: | Rima Wakim, Marwa Shehab, Ghenwa K. Dakdouki, Zeina A. Kanafani, Ghassan Dbaibo, Mohamad Zaatari, George F. Araj, Ghassan M. Matar, Kedak Baltajian, Nisreen Sidani, Souha S. Kanj, Tania A. Baban |
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Rok vydání: | 2015 |
Předmět: |
Adult
Adolescent medicine.drug_class Cephalosporin Enteric fever Molecular typing Salmonella typhi Article Typhoid fever Microbiology Food borne diseases Antibiotic resistance Drug Resistance Multiple Bacterial Ampicillin Genotype medicine Humans Lebanon Child Aged Aged 80 and over Middle east business.industry Sulfamethoxazole lcsh:Public aspects of medicine Infant lcsh:RA1-1270 Middle Aged medicine.disease bacterial infections and mycoses Virology Trimethoprim Child Preschool Water Microbiology business medicine.drug |
Zdroj: | Journal of Epidemiology and Global Health, Vol 5, Iss 2 (2019) Journal of Epidemiology and Global Health Journal of Epidemiology and Global Health, Vol 5, Iss 2, Pp 159-165 (2015) |
ISSN: | 2210-6006 |
DOI: | 10.1016/j.jegh.2014.07.003 |
Popis: | The objective of this study was to examine the epidemiology and the clinical manifestations of typhoid fever as well as the susceptibility and strain relatedness of Salmonella typhi isolates in Lebanon from 2006 to 2007. A total of 120 patients with typhoid fever were initially identified from various areas of the country based on positive culture results for S. typhi from blood, urine, stools, bone marrow and/or positive serology. Clinical, microbiological and molecular analysis was performed on cases with complete data available. These results indicated that drinking water was an unlikely mode of transmission of the infection. Despite increasing reports of antimicrobial resistance among S. typhi isolates, the vast majority of these isolates were susceptible to various antibiotic agents, including ampicillin, cephalosporins, quinolones, and trimethoprim/sulfamethoxazole. Molecular analysis of the isolates revealed a predominance of one single genotype with no variation in distribution across the geographical regions. |
Databáze: | OpenAIRE |
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