Clear cell hidradenoma of the breast: a case report with review of the literature

Autor: Tetsuya Takahama, Yoshiaki Rai, Taeko Kukita, Yoshihisa Umekita, Yasuyo Ohi, Mitutake Andou, Yoshiatu Sagara, Yasuaki Sagara, Aichi Yoshida, Yoshiaki Sagara, Hiroki Yoshida
Rok vydání: 2007
Předmět:
Zdroj: Breast Cancer. 14:307-311
ISSN: 1880-4233
1340-6868
DOI: 10.2325/jbcs.14.307
Popis: Clear cell hidradenoma of the breast is rare. A 55-year-old woman demonstrated a left breast tumor during follow-up examination of the right breast. Focal asymmetric density was shown on mammogram, and ultrasonography showed an intracystic tumor. Since the diagnosis was not clear on aspiration cytology, excisional biopsy was performed. The lesion was an intracystic tumor macroscopically. Histological examination demonstrated characteristic histological features of clear cell hidradenoma, such as proliferation of uniform epithelial cells, clear or slightly eosinophilic cytoplasm, and cuboidal cell-lined ductal structures. Immunohistochemically, these proliferating epithelial cells were negative for myoepithelial markers, such as alpha-smooth muscle actin, CD 10 and anti-muscle actin, but positive for p63. These features were consistent with clear cell hidradenoma.
Databáze: OpenAIRE