Accelerating autograft maturation in instrumented posterolateral lumbar spinal fusions without donor site morbidity
| Autor: | Gregory Cloud, Abraham Rogozinski, Chaim Rogozinski |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
musculoskeletal diseases
Adult medicine.medical_specialty animal structures Radiography medicine.medical_treatment Bone Morphogenetic Protein 2 Electric Stimulation Therapy Lumbar vertebrae Bone morphogenetic protein Iliac crest Bone morphogenetic protein 2 Transplantation Autologous Ilium Biological Factors Lumbar Transforming Growth Factor beta Medicine Humans Orthopedics and Sports Medicine Prospective Studies Reduction (orthopedic surgery) Bone Transplantation Lumbar Vertebrae business.industry Middle Aged musculoskeletal system Recombinant Proteins Surgery Electrodes Implanted surgical procedures operative medicine.anatomical_structure Spinal Fusion Spinal fusion embryonic structures Bone Morphogenetic Proteins Tissue and Organ Harvesting business |
| Zdroj: | Orthopedics. 32(11) |
| ISSN: | 1938-2367 |
| Popis: | Properly harvested iliac crest bone autograft applied to a meticulously prepared fusion bed produces a consistently high rate of fusion with a low incidence of donor site morbidity. Some reports advocate substituting bone morphogenic protein (BMP) for iliac crest bone autograft, but in posterolateral lumbar spinal fusion, BMP appears better suited to facilitate iliac crest bone autograft maturation than to substitute for it. In this single-center, nonrandomized, prospective study (minimum 2-year follow-up), cancellous-only iliac crest bone autograft was harvested for use in posterolateral lumbar spinal fusion. Reviewers blinded to graft condition and age assigned fusion scores to the random radiographs of 31 consecutive patients who underwent 1- to 3-level posterolateral lumbar spinal fusion using iliac crest bone autograft supplemented with either an implanted spinal fusion stimulator or BMP. There was no significant immediate or remote iliac crest bone autograft harvest morbidity, and there was a significant reduction in pain scores postoperatively (P |
| Databáze: | OpenAIRE |
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