Developing asymmetric iron and ruthenium-based cyclone complexes; complex factors influence the asymmetric induction in the transfer hydrogenation of ketones
| Autor: | Jonathan Hopewell, Jamie Godfrey, Tarn C. Johnson, Martin Wills, Jose E. D. Martins |
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| Rok vydání: | 2012 |
| Předmět: |
chemistry.chemical_classification
Ketone Organic Chemistry Chiral ligand chemistry.chemical_element Noyori asymmetric hydrogenation Planar chirality Photochemistry Transfer hydrogenation Biochemistry Asymmetric induction Ruthenium Catalysis chemistry Polymer chemistry QD Physical and Theoretical Chemistry |
| Zdroj: | Org. Biomol. Chem.. 10:134-145 |
| ISSN: | 1477-0539 1477-0520 |
| DOI: | 10.1039/c1ob06010d |
| Popis: | The preparation of a range of asymmetric iron and ruthenium-cyclone complexes, and their application to the asymmetric reduction of a ketone, are described. The enantioselectivity of ketone reduction is influenced by a single chiral centre in the catalyst, as well as by the planar chirality in the catalyst. This represents the first example of asymmetric ketone reduction using an iron cyclone catalyst. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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