T1DM complication in continuous insulin
| Autor: | Takafumi Masuda, Naoto Katakami, Naohiro Taya, Kazuyuki Miyashita, Mitsuyoshi Takahara, Ken Kato, Akio Kuroda, Munehide Matsuhisa, Iichiro Shimomura |
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| Rok vydání: | 2022 |
| Předmět: |
Glycated Hemoglobin
Injections Subcutaneous Continuous subcutaneous insulin infusion Endocrinology Diabetes and Metabolism Type 1 diabetes mellitus Pilot Projects General Medicine Pulse Wave Analysis Diabetic complication Atherosclerosis Carotid Intima-Media Thickness Diabetes Complications Diabetes Mellitus Type 1 Insulin Infusion Systems Japan Internal Medicine Humans Insulin Ankle Brachial Index Diabetic Nephropathies Retrospective Studies |
| Zdroj: | Journal of Diabetes Investigation. 13:1528-1532 |
| ISSN: | 2040-1124 2040-1116 |
| Popis: | To evaluate whether continuous subcutaneous insulin infusion attenuates the progression of diabetic complications, we retrospectively extracted data from 35 individuals who had developed type 1 diabetes mellitus aged ≤20 years and whose treatment had been changed from multiple daily injections to continuous subcutaneous insulin infusion. The annual changes in estimated glomerular filtration rate, urinary albumin excretion rate, carotid intima-media thickness and brachial-ankle pulse wave velocity during each treatment period were calculated. Although mean glycated hemoglobin under the continuous subcutaneous insulin infusion treatment was lower than that under the multiple daily injection treatment, there were no significant differences in annual changes in diabetic nephropathy and atherosclerosis between the two treatment periods. This pilot study showed that, in Japanese patients with juvenile-onset type 1 diabetes mellitus, there was no significant difference in the progression of diabetic nephropathy and atherosclerosis, at least in the early stage, between the two treatments. |
| Databáze: | OpenAIRE |
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