Probable Lymphocytic Hypophysitis Diagnosed by Short-term Serial Computed Tomography and Gallium-67 Scintigraphy —Case Report

Autor: Hideki Murakami, Takuro Hayashi, Masachika Sagoh, Yuichi Hirose
Rok vydání: 1999
Předmět:
Zdroj: Neurologia medico-chirurgica. 39:174-178
ISSN: 1349-8029
0470-8105
Popis: A 61-year-old female presented with headache, malaise, and left oculomotor nerve paralysis. Computed tomography (CT) demonstrated a diffuse pituitary mass and enlarged pituitary stalk with homogeneous contrast enhancement. Her symptoms gradually resolved without treatment. Gallium-67 scintigraphy showed abnormal uptake in the pituitary lesion. Serial CT every 2 weeks after admission showed homogeneous contrast enhancement and shrinking of the pituitary mass to a normal size 12 weeks after the onset. The final diagnosis was lymphocytic adenohypophysitis without biopsy. Recurrence has not been observed for 8 years after discharge. The patient did not need hormone replacement therapy. Histological examination is not always necessary to diagnose probable lymphocytic adenohypophysitis with the characteristic feature of rapid onset, abnormal gallium-67 uptake in the lesion, and resolution of symptoms in the acute stage with shrinking of the lesion on neuroimaging.
Databáze: OpenAIRE