Effect of Silver Nitrate Cauterisation of Nasal Mucosa on Quality-of-Life and Histology in Patients with Intractable Chronic Rhinitis
| Autor: | Nedha Joy, Lalee Varghese, Regi Kurien, Vedantam Rupa, Suganthy Rabi, Jenny Jacob |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
business.industry Chronic rhinitis Histology Mucous membrane of nose medicine.disease Gastroenterology Squamous metaplasia Silver nitrate chemistry.chemical_compound Otorhinolaryngology chemistry Quality of life Internal medicine medicine Original Article Surgery Quality-of-life business Hyaline |
| Zdroj: | Indian Journal of Otolaryngology and Head & Neck Surgery |
| ISSN: | 0973-7707 2231-3796 |
| DOI: | 10.1007/s12070-021-02773-9 |
| Popis: | Patients with chronic rhinitis causing intractable sneezing which is non-responsive to conventional medication require alternative therapies. The aim of the study was to ascertain the effect of topical 10% silver nitrate solution on the inferior turbinate mucosa as well as quality of life in such patients. Patients with severe chronic rhinitis who failed conventional therapy had application of 10% silver nitrate solution to inferior turbinate mucosa. The number of sneezes/day and mini Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) score was noted before and 8 to 16 weeks after treatment. Pre- and post treatment turbinate biopsies were performed to assess histological changes. At baseline, 67 patients had a mean of 36.6 sneezes/day and mean mini RQLQ score of 4.0 ± 0.7. Pre-treatment biopsies showed epithelial denudation and hyalinization of basement membrane. Following 10% silver nitrate application, 64/67 (95.5%) patients showed significant reduction in number of sneezes both at 1 week (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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