Prevalence and common genotypes of HCV infection in Sudanese patients with hepatosplenic schistosomiasis
| Autor: | S. S. Fedail, Hatim Mudawi, I. A. Fletcher, H.M. Smith |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Adolescent Genotype Liver Diseases Parasitic Hepatitis C virus Helminthiasis Schistosomiasis Hepacivirus medicine.disease_cause Sudan Liver disease Seroepidemiologic Studies Virology medicine Prevalence Seroprevalence Animals Humans Aged Splenic Diseases business.industry Hepatitis C Antibodies Middle Aged medicine.disease Hepatitis C Schistosomiasis mansoni Infectious Diseases Cross-Sectional Studies Population study Female Viral disease business |
| Zdroj: | Journal of medical virology. 79(9) |
| ISSN: | 0146-6615 |
| Popis: | A cross-sectional hospital based study was carried out at the National Center for Gastrointestinal and Liver Disease in Khartoum, Sudan to determine the prevalence, common genotypes and risk factors for hepatitis C virus infection in Sudanese patients with hepatosplenic schistosomiasis. A total of 176 patients with hepatosplenic schistosomiasis were tested for HCV antibodies and 4.5% of the samples were reactive. PCR was positive in 2.3% of cases and genotype 4 was the major genotype isolated with subtypes 4, 4e, and 4c/4d. It is concluded that HCV was of low seroprevalence in the study population and that parenteral antischistosomal therapy was not a significant risk factor in transmission of infection in the Sudan. |
| Databáze: | OpenAIRE |
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