Structure of nuclear chromatin in cells of lymphoid organs and blood from mice maintained under abnormal light-dark cycle and treated with benz(a)pyrene
| Autor: | A. V. Shurlygina, L. V. Verbitskaja, V. A. Trufakin, T. V. Shanturova, I. G. Kovshik, M. V. Bitchaeva, S. V. Mitshurina, Belkin Ad |
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| Rok vydání: | 2010 |
| Předmět: |
Male
Lymphocyte Photoperiod Biology General Biochemistry Genetics and Molecular Biology Statistics Nonparametric chemistry.chemical_compound Mice Immune system medicine Benzo(a)pyrene Image Processing Computer-Assisted Animals Lymphocytes Microscopy Nuclear chromatin Dark cycle General Medicine Molecular biology Chromatin Circadian Rhythm medicine.anatomical_structure Lymphatic system chemistry Pyrene |
| Zdroj: | Bulletin of experimental biology and medicine. 149(1) |
| ISSN: | 1573-8221 |
| Popis: | We studied the effects of benzo(a)pyrene on lymphocyte chromatin in mice with experimental desynchronosis. Desynchronosis altered chromatin structure in immune system cells and suppressed the immune response. In mice with experimental desynchronosis, benzo(a)pyrene produced more pronounced changes in the chromatin structure compared to the control. It was inferred that light-dark cycle disturbances impair the resistance of organs and systems to damaging environmental factors. |
| Databáze: | OpenAIRE |
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