Atrial Arrhythmias in Patients with Severe COVID-19
| Autor: | Xinguang Chen, Xing-Xing Kang, Yeqian Zhu, Chen-Xi Yang, Kai-Yue Han, Jing Jin, Qi Qiao, Yong Du, Xun-Chao Cai, Ruo-Min Di, Gao-Feng Zhang, Fengxiang Zhang, Ying-Jia Xu |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Article Subject Coronavirus disease 2019 (COVID-19) Premature atrial contraction business.industry Bacterial pneumonia Disease Atrial arrhythmias 030204 cardiovascular system & hematology medicine.disease Comorbidity 03 medical and health sciences 0302 clinical medicine RC666-701 Internal medicine medicine Cardiology Diseases of the circulatory (Cardiovascular) system 030212 general & internal medicine medicine.symptom Cardiology and Cardiovascular Medicine Prospective cohort study business Atrial tachycardia Research Article |
| Zdroj: | Cardiology Research and Practice Cardiology Research and Practice, Vol 2021 (2021) |
| ISSN: | 2090-0597 2090-8016 |
| Popis: | The number of confirmed COVID-19 cases has increased drastically; however, information regarding the impact of this disease on the occurrence of arrhythmias is scarce. The aim of this study was to determine the impact of COVID-19 on arrhythmia occurrence. This prospective study included patients with COVID-19 treated at the Leishenshan Temporary Hospital of Wuhan City, China, from February 24 to April 5, 2020. Demographic, comorbidity, and arrhythmias data were collected from patients with COVID-19 (n = 84) and compared with control data from patients with bacterial pneumonia (n = 84) infection. Furthermore, comparisons were made between patients with severe and nonsevere COVID-19 and between older and younger patients. Compared with patients with bacterial pneumonia, those with COVID-19 had higher total, mean, and minimum heart rates (all P < 0.01 ). Patients with severe COVID-19 (severe and critical type diseases) developed more atrial arrhythmias compared with those with nonsevere symptoms. Plasma creatine kinase isoenzyme (CKMB) levels ( P = 0.01 ) were higher in the severe group than in the nonsevere group, and there were more deaths in the severe group than in the nonsevere group (6 (15%) vs. 3 (2.30%); P = 0.05 ). Premature atrial contractions (PAC) and nonsustained atrial tachycardia (NSAT) were significantly positively correlated with plasma CKMB levels but not with high-sensitive cardiac troponin I or myoglobin levels. Our data demonstrate that COVID-19 patients have higher total, mean, and minimum heart rates compared with those with bacterial pneumonia. Patients with severe or critical disease had more frequent atrial arrhythmias (including PAC and AF) and higher CKMB levels and mortality than those with nonsevere symptoms. |
| Databáze: | OpenAIRE |
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