Anterior communicating artery aneurysm paraparesis syndrome
| Autor: | Stephen W. Coons, Peter C. Johnson, C. A. Dickman, Frederick F. Marciano, Robert F. Spetzler, J. E. Bailes, Karl A. Greene |
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| Rok vydání: | 1995 |
| Předmět: |
Male
medicine.medical_specialty Subarachnoid hemorrhage Autopsy Brain Ischemia Aneurysm medicine.artery Anterior cerebral artery Humans Paralysis Medicine cardiovascular diseases Aged Retrospective Studies Neurologic Examination medicine.diagnostic_test business.industry Microcirculation Brain Intracranial Aneurysm Thrombosis Vasospasm Middle Aged Subarachnoid Hemorrhage medicine.disease Cerebral Angiography Surgery Venous thrombosis Anterior communicating artery Treatment Outcome Cerebrovascular Circulation Female Neurology (clinical) Radiology Pulmonary Embolism Tomography X-Ray Computed business Cerebral angiography |
| Zdroj: | Neurology. 45:45-50 |
| ISSN: | 1526-632X 0028-3878 |
| DOI: | 10.1212/wnl.45.1.45 |
| Popis: | Article abstract-Objective: Clinicopathologic evaluation of patients with lower extremity paraparesis/-plegia following rupture and repair of anterior communicating artery (ACoA) aneurysms. Design: Institution-based retrospective review. Setting: A tertiary neurologic referral center. Patients, participants: Seven of 101 patients with subarachnoid hemorrhage from ruptured ACoA aneurysms treated between January 1987 and December 1992. Main outcome measures: Neurologic status at latest follow-up examination. Results: All patients presented with severe hemorrhage, poor clinical grade, and intracranial hypertension. Motor deficits developed within 7 days of aneurysm rupture and persisted for a mean duration of 39 days. Angiographic evidence of vasospasm in the anterior cerebral artery (ACA) distribution was documented in all cases, and paraparesis persisted beyond the angiographic resolution of vasospasm. All patients had evidence of frontal lobe dysfunction throughout their postoperative courses, and deep venous thrombosis and pulmonary emboli were common causes of morbidity and mortality. Autopsy data supported regional microvascular ischemia within the ACA distribution as the etiology of these motor deficits. Conclusions: The combination of vasospasm in the ACA distribution and lower extremity weakness associated with cognitive and affective impairment that resolves with time is common in patients with ACoA aneurysms. We propose that this constellation of clinical, radiographic, and pathologic findings be referred to as the "ACoA aneurysm paraparesis syndrome".NEUROLOGY 1995;45: 45-50 |
| Databáze: | OpenAIRE |
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