Triblock peptide–oligonucleotide chimeras (POCs): programmable biomolecules for the assembly of morphologically tunable and responsive hybrid materials
| Autor: | SonBinh T. Nguyen, Ryan V. Thaner, Soumitra Mokashi-Punekar, Andrea D. Merg, Nathaniel L. Rosi |
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| Rok vydání: | 2017 |
| Předmět: |
chemistry.chemical_classification
Oligonucleotide Chemistry Biomolecule Vesicle Oligonucleotides Metals and Alloys Peptide Nanotechnology 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Catalysis 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials Materials Chemistry Ceramics and Composites Salts Particle Size Peptides 0210 nano-technology Hybrid material |
| Zdroj: | Chemical Communications. 53:12221-12224 |
| ISSN: | 1364-548X 1359-7345 |
| DOI: | 10.1039/c7cc07708d |
| Popis: | Triblock peptide-oligonucleotide chimeras (POCs) consisting of peptides and oligonucleotides interlinked by an organic core are presented and their assembly behaviour is investigated. Several factors influence POC assembly, resulting in the formation of either vesicles or fibres. Design rules are introduced and used to predict and alter POC assembly morphology. |
| Databáze: | OpenAIRE |
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