| Autor: |
Nicholas Lin, Amin Valiei, Geoffrey McKay, Dao Nguyen, Nathalie Tufenkji, Christopher Moraes |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
ACS Biomaterials Science & Engineering. 8:3122-3131 |
| ISSN: |
2373-9878 |
| DOI: |
10.1021/acsbiomaterials.2c00233 |
| Popis: |
Nanopillars can influence how bacterial cells attach to a surface. Herein, we investigated whether self-assembled zinc oxide (ZnO) nanopillars synthesized on glass substrates via the conventional hydrothermal route possess anti-biofouling properties either by reducing the amount of initially attached cells or promoting the detachment of cells from the surface or both. To avoid complications associated with manual intervention methods of assessing bacterial attachment on nanopillar surfaces, we implemented a microfluidic approach. In our study, we synthesized two nanopillar topographies: a low surface density of ZnO nanopillars and a high surface density of ZnO nanopillars. Next, we mounted microfluidic channels to each of these substrates. This microfluidic approach allowed us to gently flow |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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