Wolff-Chaikoff effect in a newborn: is it an overlooked problem?
| Autor: | Murat Çakmak, Meryem Albayrak, Olcay Evliyaoğlu, Didem Aliefendioğlu, Ayca Agar, Cihat Sanli |
|---|---|
| Přispěvatelé: | Kırıkkale Üniversitesi |
| Rok vydání: | 2006 |
| Předmět: |
Wolff-Chaikoff
endocrine system medicine.medical_specialty Wolff–Chaikoff effect endocrine system diseases Iodine Compounds Jaundice Thyroid Function Tests Thyroid function tests Neonate Hypothyroidism Internal medicine Humans Medicine Endocrine system medicine.diagnostic_test business.industry Thyroid Infant Newborn Transient hypothyroidism General Medicine Organification Endocrinology medicine.anatomical_structure Pediatrics Perinatology and Child Health Thyroid hormone generation Anti-Infective Agents Local Female Surgery business Hernia Umbilical Iodine Endocrine gland Hormone |
| Zdroj: | Journal of Pediatric Surgery. 41:e1-e3 |
| ISSN: | 0022-3468 |
| DOI: | 10.1016/j.jpedsurg.2006.08.041 |
| Popis: | PubMed: 17161170 Hypothyroidism is a serious endocrine disorder emerging from deficient production of thyroid hormone (thyroid gland agenesis or dysgenesis, or inborn metabolic defects of thyroid hormone production) or a defect in thyroid hormonal receptor activity. Prevention of iodine organification by means of using iodine-containing drugs or solutions is a protective mechanism for the body and is known as the Wolff-Chaikoff effect. This effect blocks thyroid hormone generation and is often transient, with thyroid hormone synthesis recovering in a few days or weeks. We present a neonate with transient thyroid dysfunction resulting from topical exposure to iodine-containing antiseptic solution. Our aim was to increase awareness that the use of antiseptic iodine solutions in neonates may result in transient hypothyroidism through the Wolff-Chaikoff effect and should be considered after the use of iodine-containing solutions or drugs. © 2006 Elsevier Inc. All rights reserved. |
| Databáze: | OpenAIRE |
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