Hypothesis: plant and fungal biocides, copper and Indian childhood liver disease
| Autor: | A R Mattocks, M S Tanner |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Liver Cirrhosis
Male Biocide Cirrhosis 030231 tropical medicine Parthenium hysterophorus Aspergillus flavus Indian childhood cirrhosis Microbiology 03 medical and health sciences Liver disease chemistry.chemical_compound 0302 clinical medicine Aflatoxins 030225 pediatrics medicine Animals Humans Mycotoxin Pyrrolizidine Alkaloids Plant Poisoning biology business.industry Crotalaria Infant food and beverages medicine.disease biology.organism_classification Milk chemistry Pediatrics Perinatology and Child Health business Copper |
| Zdroj: | Annals of Tropical Paediatrics. 7:264-269 |
| ISSN: | 1465-3281 0272-4936 |
| DOI: | 10.1080/02724936.1987.11748522 |
| Popis: | Hepatic copper accumulation is characteristic of Indian childhood cirrhosis (ICC) but in experimental animals causes only modest liver damage. Plant and fungal biocidal agents may be hepatotoxic, may increase hepatic copper concentration, and may be secreted in milk of lactating animals. Crotalaria species, Parthenium hysterophorus and Aspergillus flavus are possible contaminants of animal feeds in rural India, and we hypothesise that their products may be synergistic with copper in causing ICC. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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