The role of the BUN/albumin ratio in predicting mortality in COVID-19 patients in the emergency department
| Autor: | Zerrin Defne Dundar, Sedat Koçak, Mustafa Kursat Ayranci, Kadir Küçükceran, Abdullah Sadik Girisgin |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty 2019-20 coronavirus outbreak Coronavirus disease 2019 (COVID-19) Turkey Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Serum albumin Severity of Illness Index Article Blood Urea Nitrogen 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Internal medicine Odds Ratio Medicine Humans Hospital Mortality Blood urea nitrogen Serum Albumin Aged Retrospective Studies Aged 80 and over biology business.industry High mortality Albumin COVID-19 030208 emergency & critical care medicine General Medicine Emergency department Middle Aged In-hospital mortality Area Under Curve Emergency Medicine biology.protein Female business Emergency Service Hospital Biomarkers |
| Zdroj: | The American Journal of Emergency Medicine |
| ISSN: | 1532-8171 |
| Popis: | Introduction Due to the high mortality and spread rates of coronavirus disease 2019 (COVID-19), there are currently serious challenges in emergency department management. As such, we investigated whether the blood urea nitrogen (BUN)/albumin ratio (BAR) predicts mortality in the COVID-19 patients in the emergency department. Methods A total of 602 COVID-19 patients who were brought to the emergency department within the period from March to September 2020 were included in the study. The BUN level, albumin level, BAR, age, gender, and in-hospital mortality status of the patients were recorded. The patients were grouped by in-hospital mortality. Statistical comparison was conducted between the groups. Results Of the patients who were included in the study, 312(51.8%) were male, and their median age was 63 years (49–73). There was in-hospital mortality in 96(15.9%) patients. The median BUN and BAR values of the patients in the non-survivor group were significantly higher than those in the survivor group (BUN: 24.76 [17.38–38.31] and 14.43 [10.84–20.42], respectively [p < 0.001]; BAR: 6.7 [4.7–10.1] and 3.4 [2.5–5.2], respectively [p < 0.001]). The mean albumin value in the non-survivor group was significantly lower than that in the survivor group (3.60 ± 0.58 and 4.13 ± 0.51, respectively; p < 0.001). The area-under-the-curve (AUC) and odds ratio values obtained by BAR to predict in-hospital COVID-19 mortality were higher than the values obtained by BUN and albumin (AUC of BAR, BUN, and albumin: 0.809, 0.771, and 0.765, respectively; odds ratio of BAR>3.9, BUN>16.05, and albumin |
| Databáze: | OpenAIRE |
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