Histological evidence of reparative activity in chorioamniotic membrane following open fetal surgery for myelomeningocele
| Autor: | Ramkumar Menon, Sergio Cavalheiro, H.J. Milani, Maurício Mendes Barbosa, Marcia Marcelino de Souza Ishigai, Antonio Fernandes Moron, Natália da Silva Carvalho |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Cancer Research medicine.medical_specialty Pathology medicine.medical_treatment myelomeningocele Biology Picrosirius red 03 medical and health sciences 0302 clinical medicine Immunology and Microbiology (miscellaneous) Suture (anatomy) Fetal membrane medicine fetal membrane healing open fetal surgery Pregnancy Fetus 030219 obstetrics & reproductive medicine Spina bifida Fetal surgery Gestational age Articles General Medicine medicine.disease Surgery spina bifida 030104 developmental biology fetal membrane repair |
| Zdroj: | Experimental and Therapeutic Medicine |
| ISSN: | 1792-1015 1792-0981 |
| DOI: | 10.3892/etm.2017.4976 |
| Popis: | An increased understanding of the reparative process in fetal membrane following surgical techniques may be helpful to decrease the risks to mother and fetus and avoid adverse pregnancy outcomes. The present study discusses histological evaluation of the fetal membrane following open fetal surgery. Chorioamniotic membranes (n=10) were obtained following birth from pregnancies that underwent open fetal surgery for myelomeningocele. The collagen distribution was quantified using picrosirius-polarization method comparing the suture site with non-suture site. The differences between the collagen fiber percentages at the two sites was evaluated by the paired t-test with P |
| Databáze: | OpenAIRE |
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