Intracranial Volume Not Correlated With Severity in Trigonocephaly
| Autor: | Léon N A Van Adrichem, Otto D M Kronig, Sophia A J Kronig |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Intracranial Pressure Trigonocephaly Craniosynostoses 03 medical and health sciences 0302 clinical medicine Intracranial volume Internal medicine medicine Humans Papilledema Retrospective Studies Intracranial pressure business.industry Skull Infant Synostosis medicine.disease Otorhinolaryngology 030220 oncology & carcinogenesis Cardiology Female Intracranial Hypertension Oral Surgery medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | The Cleft Palate-Craniofacial Journal. 59:794-799 |
| ISSN: | 1545-1569 1055-6656 |
| Popis: | Objectives: Severity of trigonocephaly varies and potentially affects intracranial volume (ICV) and intracranial pressure (ICP). The aim of this study is to measure ICV in trigonocephaly patients and compare it to normative data and correlate ICV with the severity of the skull deformity according to UCSQ (Utrecht Cranial Shape Quantifier). Design: Retrospective study. Setting: Primary craniofacial center. Patients, Participants: Nineteen preoperative patients with nonsyndromic trigonocephaly (age ≤12 months). Intervention: Intracranial volume was measured on preoperative computed tomography (CT) scans by manual segmentation (OsiriX Fondation). Utrecht Cranial Shape Quantifier was used to quantify the severity of the skull deformity. When present, papilledema as sign of elevated ICP was noted. Main Outcome Measures(s): Measured ICV was compared to Lichtenberg normative cranial volume growth curves, and Pearson correlation coefficient was used to correlate UCSQ with the ICV. Results: Mean age at CT scan was 6 months (2-11). Mean measured ICV was 842 mL (579-1124). Thirteen of h19 patients (11/15 boys and 2/4 girls) had an ICV between ±2 SD curves of Lichtenberg, 2 of 19 (1/15 boys and 1/4 girls) had an ICV less than −2 SD and 4 of 19 (3/15 boys and 1/4 girls) had an ICV greater than +2 SD. Mean UCSQ severity of trigonocephaly was 2.40 (−622.65 to 1279.75). Correlation between severity and ICV was negligible (r = −0.11). No papilledema was reported. Conclusions: Measured ICV was within normal ranges for trigonocephaly patients, in both mild and severe cases. No correlation was found between severity of trigonocephaly and ICV. |
| Databáze: | OpenAIRE |
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