Significance of an Increase in Diastolic Blood Pressure During a Stress Test in Terms of Comorbidities and Long-Term Total and CV Mortality
| Autor: | Nasir Hussain, Tibor Sydó, Joseph G. Murphy, Francisco Lopez-Jimenez, Karina A Gonzalez Carta, Nóra Sydó, Ray W. Squires, Thomas G. Allison, Béla Merkely |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Databases Factual genetic structures Minnesota Diastole Blood Pressure Comorbidity 030204 cardiovascular system & hematology Risk Assessment 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Risk Factors Cause of Death Internal medicine Diabetes mellitus Internal Medicine medicine Humans cardiovascular diseases 030212 general & internal medicine Aged Retrospective Studies Cause of death Proportional hazards model business.industry Hazard ratio Odds ratio Middle Aged Prognosis medicine.disease Blood pressure Predictive value of tests Hypertension Exercise Test Cardiology Female business circulatory and respiratory physiology |
| Zdroj: | American Journal of Hypertension. 31:976-980 |
| ISSN: | 1941-7225 0895-7061 |
| DOI: | 10.1093/ajh/hpy080 |
| Popis: | BACKGROUND A decrease in diastolic blood pressure (DBP) with exercise is considered normal, but the significance of an increase in DBP has not been validated. Our aim was to determine the relationship of DBP increasing on a stress test regarding comorbidities and mortality. METHODS Our database was reviewed from 1993 to 2010 using the first stress test of a patient. Non-Minnesota residence, baseline cardiovascular (CV) disease, rest DBP 100 mm Hg, and age RESULTS Twenty thousand seven hundred sixty patients were included (51 ± 11 years, female n = 7,314). Rest/peak averaged DBP 82 ± 8/69 ± 15 mm Hg in normal vs. 79 ± 9/82 ± 9 mm Hg in borderline vs. 76 ± 9/92 ± 11 mm Hg in abnormal DBP response. There were 1,582 deaths (8%) with 557 (3%) CV deaths over 12 ± 5 years of follow-up. In patients with borderline and abnormal DBP response, odds ratios for obesity, hypertension, diabetes, and current smoking were significant, while hazard ratios for total and CV death were not significant compared with patients with normal DBP response. CONCLUSIONS DBP response to exercise is significantly associated with important comorbidities at the time of the stress test but does not add to the prognostic yield of stress test. |
| Databáze: | OpenAIRE |
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