Diclofenac-induced pseudoporphyria; an under-recognized condition?

Autor: N. Turnbull, M. Callan, R. C. D. Staughton
Rok vydání: 2014
Předmět:
Zdroj: Clinical and Experimental Dermatology. 39:348-350
ISSN: 0307-6938
DOI: 10.1111/ced.12313
Popis: Pseudoporphyria is a photodistributed bullous disorder that is clinically and histologically similar to porphyria cutanea tarda (PCT), but without abnormal porphyrin biochemistry. Renal failure, dialysis, excessive ultraviolet A and medications, particularly nonsteroidal anti-inflammatory drugs (NSAIDs), have been associated with pseudoporphyria. We report a case of diclofenac-induced pseudoporphyria in a man with psoriatic arthritis. To our knowledge, this is only the second reported case of pseudoporphyria associated with diclofenac. Diclofenac has hitherto been considered by many dermatologists as a safe alternative in NSAID-induced pseudoporphyria.
Databáze: OpenAIRE
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