The impact on health-related quality of life from non-steroidal anti-inflammatory drugs, methotrexate, or steroids in treatment for juvenile idiopathic arthritis
| Autor: | Russ Riddle, J. D. Sampson, Anne A. Morton, Marilynn Punaro, Christina N. Ryser, Richard H. Browne, Robert J. Gatchel |
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| Rok vydání: | 2005 |
| Předmět: |
musculoskeletal diseases
Male medicine.medical_specialty Adolescent Health Status Arthritis Methylprednisolone Quality of life Internal medicine Developmental and Educational Psychology medicine Humans skin and connective tissue diseases Adverse effect Child Glucocorticoids business.industry Incidence (epidemiology) Anti-Inflammatory Agents Non-Steroidal Infant medicine.disease Arthritis Juvenile Clinical trial Methotrexate Antirheumatic Agents Child Preschool Pediatrics Perinatology and Child Health Multivariate Analysis Physical therapy Quality of Life Female business Juvenile rheumatoid arthritis medicine.drug Follow-Up Studies |
| Zdroj: | Journal of pediatric psychology. 31(3) |
| ISSN: | 0146-8693 |
| Popis: | Objective To assess and compare the impact of medication treatments on health-related quality of life (HRQOL), family function, and medical status in children with juvenile idiopathic arthritis (JIA). Methods Fifty-seven children diagnosed with JIA were assessed by a pediatric rheumatologist and placed into one of three treatment groups: (1) non-steroidal anti-inflammatory; (2) methotrexate; or (3) steroids via IV methylprednisolone. Questionnaires were administered at baseline and 4-month follow-up. The attending pediatric rheumatologist provided additional medical information. Results Data document the impact of JIA on HRQOL, particularly on physical and pain domains. Steroid patients experienced improved HRQOL at follow-up relative to other groups, despite reporting more problems with side effects. Conclusion These results demonstrate positive benefits of steroids in treating JIA children, despite the greatest incidence of adverse side effects. |
| Databáze: | OpenAIRE |
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