Clinical Characteristics and Outcome of Drug‐Induced Liver Injury in the Older Patients: From the Young‐Old to the Oldest‐Old

Autor:	Rianne A. Weersink, Ismael Alvarez‐Alvarez, Inmaculada Medina‐Cáliz, Judith Sanabria‐Cabrera, Mercedes Robles‐Díaz, Aida Ortega‐Alonso, Miren García‐Cortés, Elvira Bonilla, Hao Niu, German Soriano, Miguel Jimenez‐Perez, Hacibe Hallal, Sonia Blanco, Neil Kaplowitz, M. Isabel Lucena, Raúl J. Andrade, R.J. Andrade, M.I. Lucena, C. Stephens, M. García Cortés, M. Robles Díaz, A. Ortega Alonso, J. Pinazo, B. García Muñoz, R. Alcántara, A. Hernández, M.D. García‐Escaño, I. Medina‐Cáliz, J. Sanabria‐Cabrera, I. Alvarez‐Alvarez, E. Bonilla, H. Niu, D. Di‐Zeo, E. Del Campo, M. Jiménez Pérez, R. González Grande, S. López Ortega, I. Santaella, A. Ocaña, P. Palomino, M.C. Fernández, A. Porcel, M. Casado, M. González Sánchez, M. Romero‐Gómez, R. Millán‐Domínguez, B. Fombuena, R. Gallego, J. Ampuero, J.A. del Campo, R. Calle‐Sanz, L. Rojas, A. Rojas, A. Gil Gómez, E. Vilar, G. Soriano, C. Guarner, E.M. Román, M.A. Quijada Manuitt, R.M. Antonijoan Arbos, M. Farré, E. Montané, A.L. Arellano, A.M. Barriocanal, Y. Sanz, R.M. Morillas, M. Sala, H. Masnou Ridaura, J. Sánchez Delgado, M. Vergara Gómez, H. Hallal, E. García Oltra, J.C. Titos Arcos, A. Pérez Martínez, C. Sánchez Cobarro, J.M. Egea Caparrós, A. Castiella, J. Arenas, M.I. Gomez Osua, A. Gómez García, F.J. Esandi, S. Blanco, P. Martínez Odriozola, J. Crespo, P. Iruzubieta, J. Cabezas, A. Giráldez Gallego, E. del P. Rodríguez Seguel, M. Cuaresma, M. Prieto, I. Conde Amiel, M. Berenguer, M. García‐Eliz, J.M. Moreno, P. Martínez‐Rodenas, M. Garrido, C. Oliva, E. Gómez Domínguez, L. Cabrera, L. Cuevas, M. Bruguera, P. Gines, S. Lens, J.C. García, Z. Mariño, M. Hernández Guerra, M. Moreno San Fiel, C. Boada Fernández del Campo, J. Fuentes Olmo, E.M. Fernández Bonilla, F. Jorquera, J. González Gallego
Rok vydání:	2020
Předmět:	Adult Male medicine.medical_specialty Adolescent Hígado - Enfermedades Comorbidity elderly Severity of Illness Index 030226 pharmacology & pharmacy Culprit oldest-old Young Adult 03 medical and health sciences Liver disease Sex Factors 0302 clinical medicine Levofloxacin Internal medicine medicine Humans Pharmacology (medical) Ticlopidine Child Aged Aged 80 and over Pharmacology Polypharmacy business.industry Age Factors Odds ratio Middle Aged Jaundice medicine.disease mortality lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4] Spain 030220 oncology & carcinogenesis comorbitity Female Chemical and Drug Induced Liver Injury medicine.symptom business drug-induced liver injury Cholestatic medicine.drug
Zdroj:	Clinical Pharmacology and Therapeutics, 109, 4, pp. 1147-1158 RIUMA. Repositorio Institucional de la Universidad de Málaga instname Clinical Pharmacology and Therapeutics, 109, 1147-1158
ISSN:	1532-6535 0009-9236 1147-1158
DOI:	10.1002/cpt.2108
Popis:	Old patients with hepatotoxicity have been scarcely studied in idiosyncratic drug-induced liver injury (DILI) cohorts. We sought for the distinctive characteristics of DILI in older patients across age groups. A total of 882 DILI patients included in the Spanish DILI Registry (33% ≥65 years) were categorized according to age: “young” (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4343f3e3548bb6318764b253e03bca4b https://doi.org/10.1002/cpt.2108 Zobrazit plný text záznamu Plný text