Prevention of Bradycardia during Spinal Anesthesia under Dexmedetomidine Sedation in Older Adults

Autor:	Seyoon Kang, Yun Jeong Chae, Sun Kyung Park, Taek Geun Kim, Han Bum Joe
Rok vydání:	2022
Předmět:	dexmedetomidine spinal anesthesia bradycardia geriatric pretreatment General Medicine
Zdroj:	Journal of Clinical Medicine; Volume 11; Issue 21; Pages: 6349
ISSN:	2077-0383
DOI:	10.3390/jcm11216349
Popis:	Older adults exhibit reduced physiological responses to beta-adrenergic stimulation and parasympathetic inhibition. This study aimed to investigate the effect of reducing the incidence of bradycardia in the atropine and ephedrine pretreatment group compared to the control group in older adults who received spinal anesthesia with intravenous dexmedetomidine. Overall, 102 older adults aged over 65 years were randomly divided into three groups, and saline (control group), atropine at 0.5 mg (atropine group), and ephedrine at 8 mg (ephedrine group) were administered intravenously to each group as pretreatment. Immediately after spinal anesthesia, dexmedetomidine loading and study drug injections were commenced. The primary outcome was the incidence of bradycardia (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::433eda6dfe0263a0f01d314ec06757ee https://doi.org/10.3390/jcm11216349 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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