A comparison of pulse oximetry and cerebral oxygenation in children with severe sleep apnea-hypopnea syndrome: a pilot study

Autor: Sonia Khirani, Philippe Pouard, Brigitte Fauroux, Alessandro Amaddeo, Lucie Griffon, Jorge Olmo Arroyo, Livio De Sanctis
Rok vydání: 2017
Předmět:
Zdroj: Journal of Sleep Research. 26:799-808
ISSN: 0962-1105
DOI: 10.1111/jsr.12561
Popis: Summary Near infrared spectroscopy (NIRS) has been used to assess the impact of obstructive sleep apnea–hypopnea syndrome (OSAHS) on cerebral oxygenation. However, the relationship between the variations in the cerebral tissue oxygen saturation (ΔTOI) and pulse oximetry (ΔSpO2) has not been assessed in children with OSAHS. Consecutive clinically stable children with severe OSAHS [apnea–hypopnea index (AHI) >15 events h−1] diagnosed during a night-time polygraphy with simultaneous recording of cerebral oxygenation with NIRS (NIRO-200NX, Hamamatsu Photonics KK) were included between September 2015 and June 2016. Maximal ΔSpO2 (SpO2 drop from the value preceding desaturation to nadir) and concomitant variations in transcutaneous carbon dioxide (ΔPtcCO2), maximal ΔTOI and maximal variations in cerebral oxygenated (O2Hb) and deoxygenated (HHb) haemoglobin were reported. The relationships between ΔSpO2, ΔPtcCO2 and ΔTOI, ΔO2Hb and ΔHHb were investigated. The data from five children (three boys, aged 9.6 ± 6.7 years, AHI 16–91 events h−1) were analysed. Strong correlations were found between ΔSpO2 and ΔTOI (r = 0.887, P
Databáze: OpenAIRE