The effect of electrical stimulation on colonic transit following spinal cord injury in cats
| Autor: | Ali Keshavarzian, Lisa Riedy, Keith Bruninga, James S. Walter |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Male
medicine.medical_specialty Colon medicine.medical_treatment Electric Stimulation Therapy Stimulation Central nervous system disease medicine Carnivora Animals Gastrointestinal Transit Spinal cord injury Spinal Cord Injuries biology business.industry digestive oral and skin physiology Fissipedia Laminectomy General Medicine medicine.disease biology.organism_classification Spinal cord Electric Stimulation digestive system diseases Surgery Catheter medicine.anatomical_structure Neurology Anesthesia Cats Neurology (clinical) business Constipation |
| Zdroj: | Spinal Cord. 36:847-853 |
| ISSN: | 1476-5624 1362-4393 |
| DOI: | 10.1038/sj.sc.3100728 |
| Popis: | The effect of direct electrical stimulation on colinic transit and manometric recordings following spinal cord injury were assessed in five adult male cats. Intra-colonic catheters were surgically placed, stimulating electrodes were sutured to the colonic serosa and a laminectomy with spinal cord clamping at a T4 level was done to induce spinal cord injury (SCI). Twenty radiopaque markers were inserted through an intra-colonic catheter located 1 cm distal to the cecum and were monitored with daily fluoroscopy as a measure of colonic transit. Transit measurements were compared before SCI, after SCI and after SCI with electrical stimulation of 40 pps, 1 ms, and 0-50 mA. Colonic transit following SCI was significantly prolonged (P |
| Databáze: | OpenAIRE |
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