Randomized Controlled Trial of a Healthy Brain Ageing Cognitive Training Program: Effects on Memory, Mood, and Sleep
| Autor: | Nicole Cockayne, Louisa Norrie, Simon J.G. Lewis, Ian B. Hickie, Matthew Paradise, Daniel F. Hermens, Loren Mowszowski, Keri Diamond, Sharon L. Naismith |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Aging medicine.medical_specialty medicine.medical_treatment Neuropsychological Tests law.invention Randomized controlled trial Memory law Psychoeducation medicine Humans Dementia Single-Blind Method Aged Psychiatric Status Rating Scales Cognitive Behavioral Therapy General Neuroscience Neuropsychology Cognition General Medicine Middle Aged Verbal Learning medicine.disease Cognitive training Affect Psychiatry and Mental health Clinical Psychology Treatment Outcome Mood Physical therapy Female Geriatrics and Gerontology Verbal memory Sleep Psychology Clinical psychology |
| Zdroj: | Journal of Alzheimer's Disease. 44:1181-1191 |
| ISSN: | 1875-8908 1387-2877 |
| DOI: | 10.3233/jad-142061 |
| Popis: | Background: With the rise in the ageing population and absence of a cure for dementia, cost-effective prevention strategies for those 'at risk' of dementia including those with depression and/or mild cognitive impairment are urgently required. Objective: This study evaluated the efficacy of a multifaceted Healthy Brain Ageing Cognitive Training (HBA-CT) program for older adults 'at risk' of dementia. Methods: Using a single-blinded design, 64 participants (mean age = 66.5 years, SD = 8.6) were randomized to an immediate treatment (HBA-CT) or treatment-as-usual control arm. The HBA-CT intervention was conducted twice-weekly for seven weeks and comprised group-based psychoeducation about cognitive strategies and modifiable lifestyle factors pertaining to healthy brain ageing, and computerized cognitive training. Results: In comparison to the treatment-as-usual control arm, the HBA-CT program was associated with improvements in verbal memory (p = 0.03), self-reported memory (p = 0.03), mood (p = 0.01), and sleep (p = 0.01). While the improvements in memory (p = 0.03) and sleep (p = 0.02) remained after controlling for improvements in mood, only a trend in verbal memory improvement was apparent after controlling for sleep. Conclusion: The HBA-CT program improves cognitive, mood, and sleep functions in older adults 'at risk' of dementia, and therefore offers promise as a secondary prevention strategy. © 2015 IOS Press and the authors. All rights reserved. |
| Databáze: | OpenAIRE |
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