Medication, hospitalizations and mortality in 5 years after first-episode psychosis in a Swedish nation-wide cohort
| Autor: | Pontus Strålin, Jerker Hetta |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Pediatrics Adolescent Population Patient Readmission Cohort Studies Young Adult 03 medical and health sciences 0302 clinical medicine Risk Factors Cause of Death Epidemiology medicine Humans Young adult education Biological Psychiatry Cause of death Sweden First episode education.field_of_study business.industry Incidence Incidence (epidemiology) Middle Aged 030227 psychiatry Hospitalization Suicide Psychiatry and Mental health Psychotic Disorders Cohort Female Pshychiatric Mental Health business Self-Injurious Behavior 030217 neurology & neurosurgery Antipsychotic Agents Follow-Up Studies Cohort study |
| Zdroj: | Early Intervention in Psychiatry. 13:902-907 |
| ISSN: | 1751-7885 |
| DOI: | 10.1111/eip.12697 |
| Popis: | AIM To investigate medication, rehospitalizations and mortality after first-episode hospital-treated psychosis. METHODS A population-based nation-wide cohort (n = 2488) with a first hospitalization for psychosis at ages between 16 and 25 was identified. Cases were followed for up to 5 years after the first psychosis hospitalization with regard to mortality, hospitalizations and dispensations of antipsychotics and benzodiazepines. RESULTS The proportion of patients dispensing antipsychotics decreased from 80% year 1 after first discharge to 55% year 5. The proportion of patients having episodes of inpatient care also decreased year by year from 46% year 1 to 27% year 5. Of 863 cases with 5 years of observation time 41% had dispensations of antipsychotics every year; 21% had no dispensation of antipsychotics or hospitalization after the first year. The cumulative 5-year mortality was 3.9%. Cumulative suicide mortality was 2.4%. Incidence of suicide was highest in the first year. Male gender, benzodiazepines, recent hospital-discharge and self-harm were identified as risk factors for suicide. CONCLUSIONS The proportion of cases dispensing antipsychotics decreases year by year after first discharge. Mortality and rates of rehospitalization also decrease year by year from high levels the first year. |
| Databáze: | OpenAIRE |
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