Acute And Chronic Impact Of Cardiovascular Events On Health State Utilities
| Autor: | Brett E Fenster, David Feeny, M Lothgren, Louis S. Matza, Katie D. Stewart, Philip R Delio, Shravanthi R. Gandra, Jessica B Jordan, Evan W Davies |
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| Rok vydání: | 2016 |
| Předmět: |
Gerontology
Adult Male medicine.medical_specialty Acute coronary syndrome Health Status Population Pilot Projects Heart failure Health informatics Time-trade-off Health administration Interviews as Topic Young Adult Quality of life Utility London Humans Medicine Acute Coronary Syndrome education Stroke Qualitative Research Aged education.field_of_study Cost-utility business.industry Public health Health Policy Public Health Environmental and Occupational Health Middle Aged Cardiovascular disease Time trade-off medicine.disease Models Economic Scotland Emergency medicine Chronic Disease Quality of Life Female Medical emergency State (computer science) business Research Article |
| Zdroj: | BMC Health Services Research |
| ISSN: | 1524-4733 |
| Popis: | Background Cost-utility models are frequently used to compare treatments intended to prevent or delay the onset of cardiovascular events. Most published utilities represent post-event health states without incorporating the disutility of the event or reporting the time between the event and utility assessment. Therefore, this study estimated health state utilities representing cardiovascular conditions while distinguishing between acute impact including the cardiovascular event and the chronic post-event impact. Methods Health states were drafted and refined based on literature review, clinician interviews, and a pilot study. Three cardiovascular conditions were described: stroke, acute coronary syndrome (ACS), and heart failure. One-year acute health states represented the event and its immediate impact, and post-event health states represented chronic impact. UK general population respondents valued the health states in time trade-off tasks with time horizons of one year for acute states and ten years for chronic states. Results A total of 200 participants completed interviews (55% female; mean age = 46.6 y). Among acute health states, stroke had the lowest utility (0.33), followed by heart failure (0.60) and ACS (0.67). Utility scores for chronic health states followed the same pattern: stroke (0.52), heart failure (0.57), and ACS (0.82). For stroke and ACS, acute utilities were significantly lower than chronic post-event utilities (difference = 0.20 and 0.15, respectively; both p |
| Databáze: | OpenAIRE |
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