United airways: the impact of chronic rhinosinusitis and nasal polyps in bronchiectasic patient’s quality of life
| Autor: | J Mullol, Laura Pujols, Manuel Bernal-Sprekelsen, César Picado, Josep Roca, Jose Maria Guilemany, J. Angrill, Silvia Centellas, Eduard Prades, Isam Alobid |
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| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty High-resolution computed tomography Immunology Gastroenterology Nasal Polyps Quality of life Surveys and Questionnaires Internal medicine Humans Immunology and Allergy Medicine Nasal polyps Sinusitis Respiratory system Nose Rhinitis Bronchiectasis medicine.diagnostic_test business.industry Respiratory disease Middle Aged medicine.disease Surgery medicine.anatomical_structure Chronic Disease Quality of Life Female business |
| Zdroj: | Allergy. 64:1524-1529 |
| ISSN: | 1398-9995 0105-4538 |
| DOI: | 10.1111/j.1398-9995.2009.02011.x |
| Popis: | The nose and the bronchi belong, in anatomical and physiopathological terms, to the concept of united airways. Associations between upper and lower airways diseases have been demonstrated in allergic rhinitis and asthma, nasal polyposis (NP) and asthma, chronic rhinosinusitis (CRS) and chronic obstructive pulmonary disease, and more recently CRS/NP and bronchiectasis (BQ).To evaluate the impact of CRS on quality of life (QoL) of patients with BQ, and to correlate these findings with the pulmonary status, nasal symptoms, and general health status.In a prospective study, patients with BQ (n = 80) were evaluated for CRS and NP using EP(3)OS criteria, and severity of BQ using chest high resolution computed tomography (HRCT)-scan. Quality of life was assessed in all patients by using specific [Sinonasal Outcome Test-20 (SNOT-20), St George Respiratory Questionnaire (SGRQ)], and generic (Short Form-36; SF-36) questionnaires.Using SNOT-20, patients with CRS had worse QoL (2.1 +/- 0.1; P0.001) than patients without CRS (0.4 +/- 0.06). Using SGRQ total score, patients with CRS had worse QoL (43.7 +/- 2.2; P0.001) than patients without CRS (24.7 +/- 2.5). Using SF-36, patients with CRS had worse QoL, both in the physical summary (64 +/- 3.4; P0.05) and the mental summary (65.5 +/- 4.7; P0.05), than patients without CRS (physical summary [PS]: 76.2 +/- 3.3; mental summary [MS]: 78.3 +/- 5.3, respectively). Sinonasal Outcome Test-20 was correlated with SGRQ total score (r = 0.72; P0.01), and SF-36 physical summary (r = -0.63; P0.01). St George Respiratory Questionnaire was correlated with SF-36 on physical summary (r = -0.58; P0.05) and with forced expiratory volume in 1 s (r = -0.41; P0.05).These results suggested that CRS, measured by both specific and generic questionnaires, has a considerable impact on the QoL of patients with BQ. |
| Databáze: | OpenAIRE |
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