Brucella suis biovar 2 infection in humans in France: emerging infection or better recognition?

Autor: Alexandra Mailles, M Ogielska, V Nasser, Virginie Mick, A Creuwels, Bruno Garin-Bastuji, H de Valk, Jean-Philippe Lavigne, Maryne Jay, Z Burnusus, P Guiet, Florent Valour, M P Danjean, David O'Callaghan, B Tourrand, Véronique Vaillant, F Kemiche, M. Maurin, N Brieu
Přispěvatelé: Santé publique France - French National Public Health Agency [Saint-Maurice, France], Centre Hospitalier de Blois (CHB), Centre Hospitalier René Dubos [Pontoise], Laboratoire de santé animale, sites de Maisons-Alfort et de Dozulé, Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Centre Hospitalier du Pays d'Aix, Centre hospitalier de Sens, Centre Hospitalier d'Agen, Centre Hospitalier Alès-Cévennes, Hospices Civils de Lyon (HCL), CHU Grenoble, Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Virulence bactérienne et maladies infectieuses (VBMI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Santé publique France, Laboratoire de Diagnostic Biologique des Maladies Infectieuses et d'Hygiène, Laboratoire Adaptation et pathogénie des micro-organismes [Grenoble] (LAPM), Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Trinity College Dublin, Institut de Veille Sanitaire (INVS), Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), Département des Maladies Infectueuses
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Epidemiology and Infection
Epidemiology and Infection, Cambridge University Press (CUP), 2017, 145 (13), pp.2711-2716. ⟨10.1017/S0950268817001704⟩
Epidemiology and Infection, Cambridge University Press (CUP), 2017, 145 (13), pp.2711-2716
Epidemiol Infect
ISSN: 0950-2688
1469-4409
DOI: 10.1017/S0950268817001704⟩
Popis: SUMMARYBrucellosis is usually acquired by humans through contact with infected animals or the consumption of raw milk from infected ruminants.Brucella suisbiovar 2 (BSB2) is mainly encountered in hares and wild boars (Sus scrofa), and is known to have very low pathogenicity to humans with only two case reports published in the literature. Human cases of brucellosis caused by BSB2 were identified through the national mandatory notification of brucellosis. The identification of the bacterium species and biovar were confirmed by the national reference laboratory. Epidemiological data were obtained during medical follow-up visits. Seven human cases were identified between 2004 and 2016, all confirmed by the isolation of BSB2 in clinical specimens. All patients had direct contact with wild boars while hunting or preparing wild boar meat for consumption. Five patients had chronic medical conditions possibly responsible for an increased risk of infection. Our findings suggest that BSB2 might be an emerging pathogen in hunters with massive exposure through the dressing of wild boar carcasses. Hunters, especially those with chronic medical conditions, should be informed about the risk of BSB2 infection and should receive information on protective measures.
Databáze: OpenAIRE
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