Further Develop 1,3,4-Thiadiazole Based Probe to Effectively Detect 2,4,6-Trinitrophenol with the Help of DFT Calculations

Autor:	Xuejiao Li, Yanxin Hu, Weijie Huang, Weiran Li, Ge Gao, Chengwei Lü, Yue An
Rok vydání:	2022
Předmět:	Clinical Psychology Spectrometry Fluorescence Sociology and Political Science Picrates Clinical Biochemistry Thiadiazoles Law Biochemistry Spectroscopy Social Sciences (miscellaneous) Density Functional Theory
Zdroj:	Journal of fluorescence. 32(4)
ISSN:	1573-4994
Popis:	Four fluorimetric probes had been developed to rapidly detect 2,4,6-trinitrophenol (TNP). They were designed and synthesized on the basis of 1,3,4-thiadiazole framework combining calculation with experiment. Among them, SK-1 displayed strong blue emission with fluorescence quantum yield as high as 63.6% in solution. Further evaluation demonstrated that SK-1 displays good selectivity and high sensitivity for rapid and visual detection of TNP. It brought significant changes in both colour and fluorescence emission spectrum. The detection limit was as low as 38 nM. Quenching mechanism was confirmed as photo-induced electron transfer (PET) by nuclear magnetic titration and DFT calculations. What's more, application in real water samples and solid phase paper tests illustrated the practical significance of detection of TNP in both vapor and solution.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430d34da3f5a15caa4965a7c5973d698 https://pubmed.ncbi.nlm.nih.gov/35587852 Zobrazit plný text záznamu Full text from SpringerLink