A study of the effects of physical dermabrasion combined with chemical peeling in porcine skin
| Autor: | Jeong Hwee Choi, Jong Min Park, Dong Hye Suh, Sang Jun Lee, Min Kyung Shin, Ki-Heon Jeong, Boo Kyoung Kang |
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| Rok vydání: | 2014 |
| Předmět: |
Male
Vascular Endothelial Growth Factor A medicine.medical_specialty genetic structures Swine medicine.medical_treatment Antigens CD34 Cell Count Dermatology Combined treatment Chemexfoliation Epidermal growth factor Skin Physiological Phenomena medicine Stratum corneum Animals Rejuvenation Porcine skin Mast Cells Neurotensin Skin Epidermal Growth Factor integumentary system business.industry Dermabrasion Water jet Fibroblasts Combined Modality Therapy medicine.anatomical_structure Chemical peeling Fibroblast Growth Factor 2 Surgery Swelling medicine.symptom business Biomedical engineering |
| Zdroj: | Journal of Cosmetic and Laser Therapy. 17:24-30 |
| ISSN: | 1476-4180 1476-4172 |
| DOI: | 10.3109/14764172.2014.968580 |
| Popis: | Many comparative studies of chemical peeling and dermabrasion have been reported. However, rare basic scientific data about the immediate effects after combined treatment with chemical peeling and dermabrasion have been confirmed.The aim of this study is to evaluate the effect of the application of physical abrasion in combination with chemical peels.Three pigs were treated with physical abrasion using a water jet device in combination with an α-hydroxy acid solution, and the skin samples of the control received chemical peeling solution alone. The levels of growth factors and neuropeptides were measured with a multiplex immunoassay.Skin treated with physical dermabrasion combined with chemical peeling showed prominent detachment and swelling of the stratum corneum (SC), and fluid collection in the hair follicles. The mean cell count of CD34 positive fibroblasts and mast cells, levels of epidermal growth factor, fibroblast growth factor-2, vascular endothelial growth factor, and neurotensin, were significantly increased in the tissue treated with physical abrasion combined with a chemical peeling agent, compared to the skin in the control.We concluded that physical dermabrasion combined with chemical peeling can be more effective than chemical peeling alone, for the approach through transfollicular routes. |
| Databáze: | OpenAIRE |
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