Bioactivity Performance of Pure Mg after Plasma Electrolytic Oxidation in Silicate-Based Solutions
| Autor: | Oleksandr Oleshko, Bohdan Dryhval, Sahin Altundal, Viktoriia Korniienko, Maksym Pogorielov, Oleg Mishchenko, Wojciech Simka, Roman Viter, Yevheniia Husak, Joanna Michalska, Karlis Grundsteins |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Luminescence
Plasma Gases Pharmaceutical Science Sodium silicate 02 engineering and technology magnesium 01 natural sciences degradation rate Analytical Chemistry chemistry.chemical_compound Coated Materials Biocompatible Coating Drug Discovery Magnesium Phosphorus Plasma electrolytic oxidation 021001 nanoscience & nanotechnology Anti-Bacterial Agents Body Fluids Solutions Chemistry (miscellaneous) Sodium hydroxide Molecular Medicine 0210 nano-technology Oxidation-Reduction Staphylococcus aureus Materials science plasma electrolytic oxidation Cell Survival Oxide chemistry.chemical_element Microbial Sensitivity Tests engineering.material 010402 general chemistry Electrolysis Article Corrosion lcsh:QD241-441 biocompatibility lcsh:Organic chemistry Cell Line Tumor Humans Physical and Theoretical Chemistry antibacterial properties Electrodes Anodizing Silicates Organic Chemistry Spectrometry X-Ray Emission 0104 chemical sciences silicate bath chemistry engineering Calcium Nuclear chemistry |
| Zdroj: | Molecules Volume 26 Issue 7 Molecules, Vol 26, Iss 2094, p 2094 (2021) |
| ISSN: | 1420-3049 |
| Popis: | The biodegradable metals, including magnesium (Mg), are a convenient alternative to permanent metals but fast uncontrolled corrosion limited wide clinical application. Formation of a barrier coating on Mg alloys could be a successful strategy for the production of a stable external layer that prevents fast corrosion. Our research was aimed to develop an Mg stable oxide coating using plasma electrolytic oxidation (PEO) in silicate-based solutions. 99.9% pure Mg alloy was anodized in electrolytes contained mixtures of sodium silicate and sodium fluoride, calcium hydroxide and sodium hydroxide. Scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), contact angle (CA), Photoluminescence analysis and immersion tests were performed to assess structural and long-term corrosion properties of the new coating. Biocompatibility and antibacterial potential of the new coating were evaluated using U2OS cell culture and the gram-positive Staphylococcus aureus (S. aureus, strain B 918). PEO provided the formation of a porous oxide layer with relatively high roughness. It was shown that Ca(OH)2 was a crucial compound for oxidation and surface modification of Mg implants, treated with the PEO method. The addition of Ca2+ ions resulted in more intense oxidation of the Mg surface and growth of the oxide layer with a higher active surface area. Cell culture experiments demonstrated appropriate cell adhesion to all investigated coatings with a significantly better proliferation rate for the samples treated in Ca(OH)2-containing electrolyte. In contrast, NaOH-based electrolyte provided more relevant antibacterial effects but did not support cell proliferation. In conclusion, it should be noted that PEO of Mg alloy in silicate baths containing Ca(OH)2 provided the formation of stable biocompatible oxide coatings that could be used in the development of commercial degradable implants. |
| Databáze: | OpenAIRE |
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