Bioactive glass granules: a suitable bone substitute material in the operative treatment of depressed lateral tibial plateau fractures: a prospective, randomized 1 year follow-up study
Autor: | Allan J. Aho, Timo Kyyrönen, Juha Kukkonen, Kimmo Mattila, Susanna Moisander, Jouni T. Heikkilä |
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Rok vydání: | 2011 |
Předmět: |
Adult
Male medicine.medical_specialty Materials science Compressive Strength Radiography Biomedical Engineering Biophysics Lateral tibial plateau Dentistry Bioengineering Physical examination Bone healing Iliac crest law.invention Biomaterials Randomized controlled trial law medicine Humans Prospective Studies Prospective cohort study Aged Aged 80 and over Fracture Healing Tibia medicine.diagnostic_test business.industry Middle Aged Surgery Tibial Fractures medicine.anatomical_structure Bioactive glass Bone Substitutes Female Glass Stress Mechanical business Follow-Up Studies |
Zdroj: | Journal of Materials Science: Materials in Medicine. 22:1073-1080 |
ISSN: | 1573-4838 0957-4530 |
DOI: | 10.1007/s10856-011-4272-0 |
Popis: | Purpose of this study was to compare bioactive glass and autogenous bone as a bone substitute material in tibial plateau fractures. We designed a prospective, randomized study consisting of 25 consecutive operatively treated patients with depressed unilateral tibial comminuted plateau fracture (AO classification 41 B2 and B3).14 patients (7 females, 7 males, mean age 57 years, range 25-82) were randomized in the bioglass group (BG) and 11 patients (6 females, 5 males, mean age 50 years, range 31-82) served as autogenous bone control group (AB). Clinical examination of the patients was performed at 3 and 12 months, patients' subjective and functional results were evaluated at 12 months. Radiological analysis was performed preoperatively, immediately postoperatively and at 3 and 12 months. The postoperative redepression for both studied groups was 1 mm until 3 months and remained unchanged at 12 months. No differences were identified in the subjective evaluation, functional tests and clinical examination between the two groups during 1 year follow-up. We conclude that bioactive glass granules can be clinically used as filler material instead of autogenous bone in the lateral tibial plateau compression fractures. |
Databáze: | OpenAIRE |
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