Pre- and Perinatal Correlates of Ideal Cardiovascular Health during Early Childhood: A Prospective Analysis in the Healthy Start Study

Autor: Dana Dabelea, Wei Perng, Caylor Schuldt, Katherine A. Sauder, Gregory Barbosa, Ellen C. Francis
Rok vydání: 2021
Předmět:
Zdroj: J Pediatr
ISSN: 0022-3476
DOI: 10.1016/j.jpeds.2021.03.014
Popis: OBJECTIVES: To characterize prevalence of ideal cardiovascular health (ICVH) during early childhood (4–7 years), and to identify pre- and perinatal biological, sociodemographic, metabolic, and behavioral correlates of ICVH. STUDY DESIGN: Among 350 mother-child pairs in the Healthy Start Study, we defined ICVH as no exposure to second hand smoke (SHS), ≥1 h/day of moderate-to-vigorous physical activity, BMI≤85(th) percentile; systolic and diastolic blood pressure85%) children met criteria for SHS, BMI, blood pressure, cholesterol, and glucose, and only 1/3 met criteria for physical activity (31.4%) and diet (35.1%). In multivariable analyses, key correlates of ICVH were maternal weight status (OR(overweight/obese vs. non-overweight/obese)=0.41 [0.23, 0.73]) and offspring sex (OR(male vs. female)=2.14 [1.22, 3.65]). CONCLUSIONS: At age 4–7 years, ICVH prevalence is already low, with diet and adequate physical activity being the limiting factors. Healthy maternal weight prior to pregnancy and male sex are potential determinants of childhood ICVH. Additional work is required to explore associations of early-life ICVH with future health outcomes.
Databáze: OpenAIRE